Lake Titicaca (Peruvian Coast)

Titicaca, the world's highest navigable lake, is a world unto itself—a definite must-see. It's located 560 mi/900 km southeast of Lima, on the Peru/Bolivia border, at an altitude of 12,500 ft/3,812 m. One way to see Titicaca is on the 12-hour train ride from Cuzco to Puno through the Andes, a trip that reaches an elevation of more than 14,000 ft/4,265 m as you pass by farms, people's backyards, waterfalls and bleak but wondrous scenery—clear blue sky, deep blue water and dry, barren landscape.

This is an expensive tourist train and runs three or four times a week; the local train, which was notorious for thievery, no longer operates. Tourist buses also cover this route, stopping at major sights en route. They are faster and have English-speaking guides. Peruvians and tourists on a time limit take normal buses between Cusco and Puno, usually a six-hour trip.

Don't neglect the attractions on the Bolivian side of the lake. Stop overnight in Puno, an uninspiring town near the border that's one of the best places in Peru to buy Andean handicrafts—alpaca sweaters, rugs, ponchos and tapestries. (The town is also known for its colorful fiestas and folk dances.) Then continue by bus or car to Copacabana, just across the border, for Bolivian customs formalities and to tour the cathedral or take a day trip to the Isla del Sol and Isla de la Luna. With its small-village atmosphere and charm, this town is a nice overnight stay from which you can see more of the lake.

From Puno, tours or public transport are available to Taquile Island (small Inca ruins and very nice woven goods), Sillustani on Lake Umayo (to see chullpas, the funerary towers of the ancient Colla people) and the Floating Islands (actually enormous floating reed mats that support the Uros people's villages of reed huts—you can buy reed souvenirs there).

Huacachina

La Paz, Bolivia

Puno

Puno lies on the shores of Lake Titicaca. This area is the cradle of the Aymara civilization and the birthplace of the Inca Empire.

Ollantaytambo

History buffs will get a real kick out of Ollantaytambo, a pretty town about 26 mi/42 km northwest of Cusco. Before the arrival of the Spanish conquistadors, Ollantaytambo served as the royal estate and ceremonial center of the Inca ruler Pachacuti, who had previously conquered this region.

The town itself still serves as a living example of Inca urban planning, while the surrounding Inca terraces and Temple Hill provide more fine examples of Inca architecture. Ollantaytambo played an important role during the Spanish Conquest. It was here that Manco Inca Yupanqui successfully defended the Inca position against a Spanish expedition following the fall of Cusco, but later retreated to the greater security of Vilcabamba.

Visitors can easily spend a couple of days exploring the nearby archaeological sites and strolling around the town. The higher sites offer spectacular views of the mountains and valleys, while the streets of Ollantaytambo are home to pre-Columbian and colonial architecture, traditional markets and plenty of Andean character.

Cuzco (Cusco)

The Cuzco (Cusco) region of Peru combines Inca legacy with Spanish colonial architecture in an atmosphere at once provincial and sublime. The chaotic marketplaces where campesinos barter grain or potatoes for multi-colored fabric belie the mute spirituality of the Lost Cities, where Inca stonework conveys order and balance. Such diversity enhances this inspiring nine-day adventure. The blue sky radiates with an intensity achieved only at high altitudes (the city of Cuzco lies 11,150 feet above sea level), while the landscape offers its unique pattern of exacting agricultural grids and tangled jungle masses.

Colca Canyon

Deep as the Grand Canyon in the USA, Colca Canyon is a colorful Andean valley with pre-Incan roots founded by the Spaniards in the 1530s. It's claimed to be the biggest and deepest canyon in the world making it impossible to see the bottom of the valley. Inhabitants of the valley welcome guests with a range of cultural, adventurous sports, and archaeological activities.

Arequipa

Sparkling in the sun, Arequipa is called the White City because of the sillar, a white volcanic stone that makes up its buildings, modern ones as well as Spanish colonial. Peru's second-largest city sits surrounded by towering mountains—including the 19,000-ft/5,800-m volcano El Misti.

The city itself is the home of the monastery of La Recoleta (with a museum and library) and several interesting churches, but its highlight is the Santa Catalina Convent. Built in the late 16th century (but closed to the public until 1970), it was a self-contained community, a place where nuns could worship and live without leaving the convent. Walk through the well-preserved structure, soak up the peaceful atmosphere and discover the tiny, secluded plazas and lovely courtyards within.

From Arequipa, take a guided tour of Colca Canyon, one of the deepest canyons in the world (10,500 ft/3,191 m deep). (Day trips are possible, but they require many hours in a bus and are not recommended; two- or three-day trips are preferable.) Several local agencies arrange two-day trips with pleasant overnights in rural hotels. A journey to the canyon offers a view of extensive pre-Incan and Incan agricultural terracing, some of which is still farmed today, as well as a chance to see Andean condors at Cruz del Condor, a lookout point.

Adventurous travelers can follow in the footsteps of the chasqui, the Incan foot messengers, and trek the canyon. The Cotahuasi Canyon is more remote than the Colca, but it is the deepest in the world, with stretches as low as 10,857 ft/3,300 m. It is located 125 mi/200 km northwest of Arequipa. Or visit the Reserva Nacional de Salinas y Aguada Blanca, a nature reserve with stunning lakes and salt flats, located high in the surrounding mountains. The area is about 465 mi/750 km southeast of Lima by air. By road, the distances are closer to 625 mi/1,000 km.

Nazca

Nazca (Nasca) is located on the coast of southern Peru, and is the largest town in the Nazca Province. It is most famous for the Nazca Lines, the desert line drawings only visible from high elevations. Nazca is also famous for its complicated system of aqueducts, used to irrigate farmland as well as for home use, that are still functioning today.

Lima

Lima, "the City of the Kings," became the effective capital of the Viceroyalty of Peru, established 1560. Today, a visit to Lima may serve as a unique Peruvian experience that offers a glimpse into the Andean world, Spanish tradition and the country's modern aspect. Visit handsome old buildings and baroque churches that testify to the city's religious background and the Plaza de Armas, shared by the realms of the Catholic church, municipality and national government. The pre-Inca archaeological site of Pachacamac lie a short distance south of the city. Once a ceremonial site, Pachacamac has been the most important religious center of the Andean world since before the age of Christ. Stop and admire The Temple of the Sun and the Moon, Lima's outstanding museums, and Machu Picchu - a "Jewel in the Mist."